Cell BiologybioRxiv
Polarized Desmosome and Hemidesmosome Shedding via Exosomes is an Early Indicator of Outer Blood-Retina Barrier Dysfunction
B. Hernandez, N. P. Skiba, K. Ploessl…·M. Klingeborn
The paper shows that oxidative stress in RPE cells leads to exosome-mediated shedding of desmosomes and hemidesmosomes, indicating early blood-retinal barrier dysfunction.
DOI 10.1002/jex2.116