Author

A. Manenti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 7

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 5 Organism:human· 4 Assay:proteomics· 4 Research Focus:drug response / drug discovery· 2 Organism:virus· 2 Organism:mouse· 1

Frequent Co-Authors

E. Montomoli· 7 shared L. Benincasa· 4 shared E. Andreano· 3 shared E. Pantano· 3 shared G. Piccini· 3 shared I. Paciello· 3 shared N. Manganaro· 3 shared R. Rappuoli· 3 shared

Activity by Year

2020-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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7 shared papersImmunology

E. Montomoli

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Establishment and validation of a High-throughput Micro-Neutralization assay for Respiratory Syncytial Virus (subtypes A and B)

C. Bonifazi, C. M. Trombetta, I. Barneschi, S. Latanza, S. Leopoldi, L. Benincasa, M. Leonardi, C. Semplici, P. Piu, S. Marchi, E. Montomoli, A. Manenti

This paper validates a high-throughput micro-neutralization assay for detecting neutralizing antibodies against Respiratory Syncytial Virus subtypes A and B.

bioRxiv · Mar 20, 2023Immunology

Intranasal administration of a VLP-based vaccine against COVID-19 induces neutralizing antibodies against SARS-CoV-2 and Variants of Concerns

D. A. Rothen, P. S. Krenger, A. Nonic, I. Balke, A.-C. Vogt, X. Chang, A. Manenti, F. Vedovi, G. Resevica, S. Walton, A. Zeltins, E. Montomoli, M. Vogel, M. F. Bachmann, M. O. Mohsen

This study evaluates an intranasally administered VLP-based vaccine in a murine model, showing strong systemic and mucosal antibody responses against SARS-CoV-2 and its variants.

bioRxiv · Sep 10, 2021 · PreprintImmunology

SARS-CoV-2 escape in vitro from a highly neutralizing COVID-19 convalescent plasma

E. Andreano, G. Piccini, D. Licastro, L. Casalino, N. V. Johnson, I. Paciello, S. Dal Monego, E. Pantano, N. Manganaro, A. Manenti, R. Manna, E. Casa, I. Hyseni, L. Benincasa, E. Montomoli, , R. Rappuoli

This study shows that three mutations in SARS-CoV-2 allowed it to escape neutralization by a highly neutralizing convalescent plasma.

bioRxiv · Dec 28, 2020Immunology

The Theory and Practice of the viral dose in neutralization assay: insights on SARS-CoV-2 "doublethink" effect.

E. Molesti, A. Manenti, M. Maggetti, G. Lapini, A. Torelli, E. Montomoli

This study evaluates the impact of different viral infective doses on micro-neutralization assay results for SARS-CoV-2, finding that a lower dose improves sensitivity without compromising specificity.

bioRxiv · Oct 16, 2020Immunology

Extremely potent human monoclonal antibodies from convalescent Covid-19 patients

E. Andreano, E. Nicastri, I. Paciello, P. Pileri, N. Manganaro, G. Piccini, A. Manenti, E. Pantano, A. Kabanova, M. Troisi, F. Vacca, D. Cardamone, C. De Santi, L. Benincasa, C. Agrati, , R. Rappuoli

The paper isolates extremely potent human monoclonal antibodies from convalescent Covid-19 patients, effective against SARS-CoV-2 at low concentrations.

bioRxiv · Oct 7, 2020Immunology

Comparative analyses of SARS-CoV-2 binding (IgG, IgM, IgA) and neutralizing antibodies from human serum samples

L. Mazzini, D. Martinuzzi, I. Hyseni, G. Lapini, L. Benincasa, P. Piu, C. M. Trombetta, S. Marchi, I. Razzano, A. Manenti, E. Montomoli

This study compares SARS-CoV-2-specific antibody levels (IgG, IgM, IgA) in human serum samples using ELISA and functional neutralization assays, finding strong correlation between ELISA responses and neutralization titers.

bioRxiv · Aug 10, 2020Immunology

Identification of neutralizing human monoclonal antibodies from Italian Covid-19 convalescent patients

E. Andreano, E. Nicastri, I. Paciello, P. Pileri, N. Manganaro, G. Piccini, A. Manenti, M. Troisi, F. Vacca, E. Pantano, C. De Santi, D. Cardamone, A. Kabanova, C. Agrati, C. Castilletti, , R. Rappuoli

The paper isolates neutralizing human monoclonal antibodies from Covid-19 convalescent patients for therapeutic and prophylactic interventions.

bioRxiv · May 5, 2020 · PreprintImmunology