Optogenetic rejuvenation of mitochondrial membrane potential extends C. elegans lifespan
B. J. Berry, A. Vodickov, A. Mueller-Eigner, C. Meng, C. Ludwig, M. Kaeberlein, S. Peleg, A. P. Wojtovich
The paper demonstrates that increasing mitochondrial membrane potential in C. elegans using a light-activated proton pump extends lifespan and reverses age-related phenotypes.
bioRxiv · May 11, 2022Physiology