Author

A. N. Amin

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Evolutionary Biology· 1

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Approach:statistical model· 1

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D. Marks· 1 shared E. N. Weinstein· 1 shared J. Frazer· 1 shared

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2022-2022 · peak 1/yr

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1 shared paperEvolutionary Biology

D. Marks

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1 paper

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Evolutionary BiologybioRxivPreprintJan 29, 2022

Non-identifiability and the Blessings of Misspecification in Models of Molecular Fitness

E. N. Weinstein, A. N. Amin, J. Frazer, D. Marks

This paper shows that fitness cannot be reliably estimated from sequence data alone and that current models work well due to misspecification, not accuracy.

DOI 10.1101/2022.01.29.478324

statistical model

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