Spatially-resolved single cell transcriptomics reveal a critical role for γδ T cells in the control of skin inflammation and subcutaneous adipose wasting during chronic Trypanosoma brucei infection
J. F. Q. Alcala, M. C. Sinton, P. Chandrasegaran, A. N. Lestari, R. Heslop, B. Cheaib, J. Ogunsola, D. M. Ngoyi, N. R. K. Swar, A. Cooper, S. B. Coffelt, A. MacLeod
This study uses spatial and single-cell transcriptomics to show that γδ T cells and adipocytes collaborate to control skin inflammation and adipose tissue wasting during chronic Trypanosoma brucei infection.
bioRxiv · Mar 1, 2023 · PreprintImmunology