Author

A. O'Toole

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:Bayesian inference· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:phylogenetics / evolution· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Rambaut· 3 shared A. Bandyopadhyay· 1 shared A. Ceschi· 1 shared A. da Silva Filipe· 1 shared A. De Marco· 1 shared A. G. Shaw· 1 shared A. Khurshid· 1 shared A. Wickenhagen· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

A. Rambaut

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The circulating SARS-CoV-2 spike variant N439K maintains fitness while evading antibody-mediated immunity

E. C. Thomson, L. E. Rosen, J. G. Shepherd, R. Spreafico, A. da Silva Filipe, J. A. Wojcechowskyj, C. Davis, L. Piccoli, D. J. Pascall, J. Dillen, S. Lytras, N. Czudnochowski, R. Shah, M. Meury, N. Jesudason, , J. Nichols

The paper shows the N439K SARS-CoV-2 spike variant maintains replication fitness while evading antibody neutralization.

bioRxiv · Nov 4, 2020Microbiology

Accommodating individual travel history, global mobility, and unsampled diversity in phylogeography: a SARS-CoV-2 case study.

P. Lemey, S. Hong, V. Hill, G. Baele, C. Poletto, V. Colizza, A. O'Toole, J. T. McCrone, K. G. Andersen, M. Worobey, M. I. Nelson, A. Rambaut, M. A. Suchard

This paper integrates travel history data into Bayesian phylogeographic analysis of SARS-CoV-2 to improve virus spread reconstructions and address sampling bias.

bioRxiv · Jun 22, 2020 · PreprintEvolutionary Biology

Rapid and sensitive direct detection and identification of poliovirus from stool and environmental surveillance samples using nanopore sequencing

A. G. Shaw, M. Majumdar, C. Troman, A. O'Toole, B. Benny, D. Abraham, I. Praharaj, G. Kang, S. Sharif, M. M. Alam, S. Shaukat, M. Angez, A. Khurshid, N. Mahmood, Y. Arshad, , N. C. Grassly

This paper presents a nested PCR and nanopore sequencing protocol for rapid and sensitive detection and identification of poliovirus in stool and environmental samples, reducing the time compared to traditional cell-culture methods.

bioRxiv · Apr 27, 2020Microbiology