Subtractive Interaction Proteomics Reveal a Network of Signaling Pathways Activated by an Oncogenic Transcription Factor in Acute Myeloid Leukemia
N. Guillen, M. Wieske, A. Otto, A. A. Mian, M. Rokicki, C. Guy, C. Alvares, P. Hole, H. Held, O. G. Ottmann, D. Becher, M. Wilson, K. Heesom, M. Ruthardt, C. Chiriches
This study uses subtractive interaction proteomics to identify signaling pathways activated by the t(6;9)-DEK/CAN oncogene in AML, revealing potential therapeutic targets.
bioRxiv · Nov 7, 2018 · PreprintCancer Biology