Author

A. P. Brown

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1

Frequent Co-Authors

J. L. Kelley· 2 shared L. Arias-Rodriguez· 2 shared M. Tobler· 2 shared C. Delich· 1 shared C. Henpita· 1 shared C. M. Rodriguez Pena· 1 shared D. Lin· 1 shared G. Quon· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersEvolutionary Biology

J. L. Kelley

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3 papers

Recent·Most cited

Single-cell RNA-seq analysis reveals lung epithelial cell-specific contributions of Tet1 to allergic inflammation

T. Zhu, A. P. Brown, L. Cai, G. Quon, H. Ji

This study uses single-cell RNA-seq to show that Tet1 deletion in lung epithelial cells promotes allergen-induced inflammation by altering transcriptomic networks and cell type composition.

bioRxiv · Dec 22, 2021 · PreprintImmunology

Integrative analyses of convergent adaptation in sympatric extremophile fishes

R. S. Greenway, R. De-Kayne, A. P. Brown, H. Camarillo, C. Delich, K. L. McGowan, J. T. Nelson, L. Arias-Rodriguez, J. L. Kelley, M. Tobler

The paper examines convergent adaptation in three sympatric fish species exposed to H2S, finding convergence in traits and gene expression but not in genomic divergence patterns.

bioRxiv · Jun 28, 2021Evolutionary Biology

Convergent evolution of conserved mitochondrial pathways underlies repeated adaptation to extreme environments

R. Greenway, N. Barts, C. Henpita, A. P. Brown, L. Arias-Rodriguez, C. M. Rodriguez Pena, S. Arndt, G. Y. Lau, M. P. Murphy, L. Wu, D. Lin, J. H. Shaw, J. L. Kelley, M. Tobler

This study identifies convergent genetic and physiological adaptations in multiple fish lineages that enable tolerance to hydrogen sulfide, showing that conserved mitochondrial pathways are repeatedly modified for H2S resistance.

bioRxiv · Feb 24, 2020Evolutionary Biology