Engineering of human myotubes toward a mature metabolic and contractile phenotype
S. I. Dreher, P. Grubba, C. von Toerne, A. Moruzzi, J. Maurer, T. Goj, A. L. Birkenfeld, A. Peter, P. Loskill, S. M. Hauck, C. Weigert
This paper shows that adding IGF1 to human myoblast cultures improves their contractility and metabolic profile, making them more like mature skeletal muscle.
bioRxiv · Jun 12, 2023Cell Biology