Author

A. Pirani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:E. coli· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2

Frequent Co-Authors

E. S. Snitkin· 5 shared A. Sintsova· 2 shared K. Saund· 2 shared A. E. Frick-Cheng· 1 shared A. Frick-Cheng· 1 shared B. Henrissat· 1 shared B. Lacy· 1 shared C. M. Bassis· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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5 shared papersMicrobiology

E. S. Snitkin

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5 papers

Recent·Most cited

Vaginal microbiota of adolescents and their mothers: A preliminary study of vertical transmission and persistence

C. M. Bassis, K. A. Bullock, D. E. Sack, K. Saund, A. Pirani, E. S. Snitkin, V. I. Alaniz, E. H. Quint, V. B. Young, J. D. Bell

This study examines the vaginal microbiota of adolescent daughters and their mothers, finding that vaginal delivery is associated with similar microbiota between mothers and daughters.

bioRxiv · Jul 26, 2022 · PreprintMicrobiology

Strain variation in Clostridioides difficile toxin activity associated with genomic variation at both PaLoc and non-PaLoc loci

K. Saund, A. Pirani, B. Lacy, P. C. Hanna, E. S. Snitkin

This study identifies non-PaLoc genomic variants associated with toxin activity and other in vitro phenotypes in C. difficile using phylogenetic, statistical, and GWAS approaches.

bioRxiv · Dec 8, 2021 · PreprintMicrobiology

Ferric Citrate Uptake is a Virulence Factor in Uropathogenic Escherichia coli

A. E. Frick-Cheng, A. Sintsova, S. N. Smith, A. Pirani, E. S. Snitkin, H. L. T. Mobley

This study identifies the ferric citrate uptake system as a virulence factor in UPEC, showing its role in iron acquisition during UTI and its importance for bacterial fitness.

bioRxiv · Nov 12, 2021Microbiology

Phenotypic and genomic diversification in complex carbohydrate degrading human gut bacteria

N. A. Pudlo, K. Urs, R. Crawford, A. Pirani, T. Atherly, R. Jimenez, N. Terrapon, B. Henrissat, D. A. Peterson, C. Ziemer, E. S. Snitkin, E. Martens

The paper identifies genomic and phenotypic diversity in carbohydrate-degrading gut bacteria, showing variation in substrate utilization and evidence of gene transfer shaping metabolic capabilities.

bioRxiv · Jul 15, 2021Microbiology

Genetically diverse uropathogenic Escherichia coli adopt a common transcriptional program in patients with urinary tract infections

A. Sintsova, A. Frick-Cheng, S. Smith, A. Pirani, S. Subashchandrabose, E. S. Snitkin, H. Mobley

The paper identifies a common transcriptional program in genetically diverse UPEC strains from UTI patients, marked by upregulated translational machinery and specialized catabolism.

bioRxiv · Mar 31, 2019Microbiology