Cancer BiologybioRxivPreprint
The ratio of cytotoxic lymphocytes to M2-like macrophages is prognostic in immunogenic tumors
A. Mezheyeuski, M. Backman, J. Mattsson…·T. Sjöblom
The paper identifies a prognostic signature based on the ratio of cytotoxic lymphocytes to M2-like macrophages in tumor microenvironments, showing better survival prediction than existing immune scores in colon cancer and other high-mutation burden cancers.
DOI 10.1101/2021.03.24.436814