Impact of temperature on the affinity of SARS-CoV-2 Spike for ACE2
J. Prevost, J. Richard, R. Gasser, S. Ding, C. Fage, S. P. Anand, D. Adam, N. Gupta Vergara, A. Tauzin, M. Benlarbi, S. Y. Gong, G. Goyette, A. Prive, S. Moreira, H. Charest, , A. Finzi
This study investigates how temperature affects SARS-CoV-2 Spike protein affinity for ACE2, finding increased binding at low temperatures, which is mitigated by the N501Y mutation.
bioRxiv · Jul 9, 2021 · PreprintMicrobiology