Author

A. Tauzin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Immunology· 5 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 11 Research Focus:host-pathogen & immune response· 10 Assay:proteomics· 7 Research Focus:cell type annotation· 5 Organism:human· 5 Research Focus:clustering· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2

Frequent Co-Authors

A. Finzi· 11 shared G. Goyette· 9 shared J. Richard· 8 shared S. Y. Gong· 8 shared H. Medjahed· 7 shared J. Prevost· 7 shared M. Benlarbi· 7 shared R. Gasser· 7 shared

Activity by Year

2021-2024 · peak 9/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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11 shared papersMicrobiology

A. Finzi

Mutual co-authors in cluster

Author profile →

12 papers

Recent·Most cited

Temperature-dependent Spike-ACE2 interaction of Omicron subvariants is associated with viral transmission

M. Benlarbi, S. Ding, E. Belanger, A. Tauzin, R. Poujol, H. Medjahed, O. El Ferri, Y. Bo, C. Bourassa, J. Hussin, J. Fafard, M. Pazgier, I. Levade, C. Abrams, M. Cote, A. Finzi

This study examines how temperature affects Spike-ACE2 interactions in Omicron subvariants and links these interactions to viral transmission efficiency.

bioRxiv · Jan 20, 2024Microbiology

A third SARS-CoV-2 mRNA vaccine dose in people receiving hemodialysis overcomes B cell defects but elicits a skewed CD4+ T cell profile

G. Sannier, A. Nicolas, M. Dube, L. Marchitto, M. Nayrac, O. Tastet, A. Tauzin, R. Lima-Barbosa, M. Laporte, R. Cloutier, A. S. Flores, M. Boutin, S. Y. Gong, M. Benlarbi, S. Ding, , D. E. Kaufmann

bioRxiv · Sep 5, 2022Immunology

The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice

I. Ullah, G. Beaudoin-Bussieres, K. Symmes, M. Cloutier, E. Ducas, A. Tauzin, A. Laumaea, P. Begin, W. Mothes, R. Bazin, A. Finzi, P. D. Uchil

This study shows that CCPs with high Fc-effector activity, rather than just neutralizing ability, are more effective in treating SARS-CoV-2 in mice.

bioRxiv · Jun 10, 2022Immunology

SARS-CoV-2 Omicron Spike recognition by plasma from individuals receiving BNT162b2 mRNA vaccination with a 16-weeks interval between doses

D. Chatterjee, A. Tauzin, L. Marchitto, S. Y. Gong, M. Boutin, C. Bourassa, G. Beaudoin-Bussieres, Y. Bo, S. Ding, A. Laumaea, D. Vezina, J. Perreault, L. Gokool, C. Morrisseau, P. Arlotto, , A. Finzi

This study evaluates how plasma from individuals with a 16-week interval between BNT162b2 mRNA vaccine doses recognizes and neutralizes the Omicron Spike compared to other variants.

bioRxiv · Dec 21, 2021Microbiology

Temporal associations of B and T cell immunity with robust vaccine responsiveness in a 16-week interval BNT162b2 regimen

M. Nayrac, M. Dube, G. Sannier, A. Nicolas, L. Marchitto, O. Tastet, A. Tauzin, N. Brassard, G. Beaudoin-Bussieres, D. Vezina, S. Y. Gong, M. Benlarbi, R. Gasser, A. Laumaea, C. Bourassa, , D. E. Kaufmann

The paper examines B and T cell immunity responses to a 16-week interval BNT162b2 vaccine regimen, finding robust immune memory and functional associations between immune components.

bioRxiv · Dec 18, 2021Immunology

The dynamics of spawning acts by a semelparous fish and its associated energetic expenses

C. Tentelier, C. Bouchard, A. Bernardin, A. Tauzin, J.-C. Aymes, F. Lange, C. Recapet, J. Rives

This study tracks spawning behavior and energy expenditure in female Allis shad using accelerometry, finding they deplete energy faster than gametes and face increased mortality risk with warming waters.

Peer Community Journal · Dec 1, 2021Peer-reviewedEcology

An anti-SARS-CoV-2 non-neutralizing antibody with Fc-effector function defines a new NTD epitope and delays neuroinvasion and death in K18-hACE2 mice

G. Beaudoin-Bussieres, Y. Chen, I. Ullah, J. Prevost, W. D. Tolbert, K. Symmes, S. Ding, M. Benlarbi, S. Y. Gong, A. Tauzin, R. Gasser, D. Chatterjee, D. Vezina, G. Goyette, J. Richard, , A. Finzi

bioRxiv · Sep 8, 2021 · PreprintMicrobiology

Contribution of single mutations to selected SARS-CoV-2 emerging variants Spike antigenicity

S. Y. Gong, D. Chatterjee, J. Richard, J. Prevost, A. Tauzin, R. Gasser, Y. Bo, D. Vezina, G. Goyette, G. Gendron-Lepage, H. Medjahed, M. Roger, M. Cote, A. Finzi

The paper evaluates how single mutations in SARS-CoV-2 Spike protein affect antigenicity and ACE2 binding in emerging variants.

bioRxiv · Aug 4, 2021Microbiology

Structural Basis and Mode of Action for Two Broadly Neutralizing Antibodies Against SARS-CoV-2 Emerging Variants of Concern

W. Mothes, W. Li, Y. Chen, J. Prevost, I. Ullah, M. Lu, S. Y. Gong, A. Tauzin, R. Gasser, D. Vezina, S. P. Anand, G. Goyette, D. Chaterjee, S. Ding, W. D. Tolbert, , A. Finzi

This study characterizes two SARS-CoV-2 antibodies effective against variants, showing their structural basis and mechanisms of neutralization.

bioRxiv · Aug 2, 2021Microbiology

Impact of temperature on the affinity of SARS-CoV-2 Spike for ACE2

J. Prevost, J. Richard, R. Gasser, S. Ding, C. Fage, S. P. Anand, D. Adam, N. Gupta Vergara, A. Tauzin, M. Benlarbi, S. Y. Gong, G. Goyette, A. Prive, S. Moreira, H. Charest, , A. Finzi

This study investigates how temperature affects SARS-CoV-2 Spike protein affinity for ACE2, finding increased binding at low temperatures, which is mitigated by the N501Y mutation.

bioRxiv · Jul 9, 2021 · PreprintMicrobiology

Live imaging of SARS-CoV-2 infection in mice reveals neutralizing antibodies require Fc function for optimal efficacy

I. Ullah, J. Prevost, M. S. Ladinsky, H. Stone, M. Lu, S. P. Anand, G. Beaudoin-Bussieres, K. Symmes, M. Benlarbi, S. Ding, R. Gasser, C. Fink, Y. Chen, A. Tauzin, G. Goyette, , P. D. Uchil

This study uses live imaging to show that neutralizing antibodies against SARS-CoV-2 need both Fab and Fc functions to effectively prevent and resolve infection in mice.

bioRxiv · Mar 22, 2021Immunology

A single BNT162b2 mRNA dose elicits antibodies with Fc-mediated effector functions and boost pre-existing humoral and T cell responses

A. Tauzin, M. Nayrac, M. Benlarbi, S. Y. Gong, R. Gasser, G. Beaudoin-Bussieres, N. Brassard, A. Laumaea, D. Vezina, J. Prevost, S. P. Anand, C. Bourassa, G. Gendron-Lepage, H. Medjahed, G. Goyette, , A. Finzi

This study shows a single dose of the BNT162b2 mRNA vaccine elicits strong antibody and T cell responses, including Fc-mediated effector functions, and boosts pre-existing immunity in previously infected individuals.

bioRxiv · Mar 18, 2021 · PreprintImmunology