ImmunologybioRxiv
A crosstalk between hepcidin and IRE/IRP pathways controls ferroportinexpression and determines serum iron levels in mice
E. Charlebois, C. Fillebeen, A. Katsarou…·K. Pantopulos
This study shows that hepcidin and IRE/IRP pathways interact to regulate ferroportin expression and serum iron levels in mice, with iron affecting hepcidin's ability to induce hypoferremia.
DOI 10.7554/elife.81332