Maf1, a repressor of RNA polymerase III-dependent transcription, regulates bone mass
E. Busschers, N. Ahmad, L. Sun, J. R. Iben, C. J. Walkey, A. Rusin, T. Yuen, C. J. Rosen, I. M. Willis, M. Zaidi, D. L. Johnson
This study shows Maf1 regulates bone mass by modulating RNA polymerase III transcription, with both loss and gain of function leading to high bone mass, but through distinct mechanisms.
bioRxiv · Nov 9, 2021Cell Biology