Author

D. L. Johnson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Astrinidis· 1 shared A. Rusin· 1 shared C. J. Rosen· 1 shared C. J. Walkey· 1 shared D. L. Brooks· 1 shared D. N. Parke· 1 shared D. Oluwalana· 1 shared D. R. Layman· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCancer Biology

A. Astrinidis

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Assessing the Population Consequences of Disturbance and Climate Change for the Pacific Walrus

D. L. Johnson, J. M. Eisaguirre, R. L. Taylor, J. L. Garlich-Miller

This study develops a PCoD model for Pacific walruses to assess how climate change and anthropogenic disturbance affect population dynamics, finding that both factors reduce carrying capacity and growth rate, but mitigation efforts can lessen these impacts.

bioRxiv · Oct 12, 2023Ecology

Combination of Volasertib and Rapamycin Inhibits the Regrowth of TSC2-Deficient Tumors

M. Valianou, E. Y. Zhang, D. L. Johnson, R. Meyers, M. M. Markiewski, M. Karbowniczek, L. M. Pfeffer, J. J. Yu, J. J. Bissler, A. Astrinidis

This study shows that combining volasertib and rapamycin inhibits tumor regrowth in TSC2-deficient models more effectively than rapamycin alone.

bioRxiv · Nov 2, 2022 · PreprintCancer Biology

Maf1, a repressor of RNA polymerase III-dependent transcription, regulates bone mass

E. Busschers, N. Ahmad, L. Sun, J. R. Iben, C. J. Walkey, A. Rusin, T. Yuen, C. J. Rosen, I. M. Willis, M. Zaidi, D. L. Johnson

This study shows Maf1 regulates bone mass by modulating RNA polymerase III transcription, with both loss and gain of function leading to high bone mass, but through distinct mechanisms.

bioRxiv · Nov 9, 2021Cell Biology

HIF-dependent expression of creatine kinase brain isoform (CKB) promotes breast cancer metastasis, whereas cyclocreatine therapy impairs invasion and improves the efficacy of conventional chemotherapies

R. I. Krutilina, H. C. Playa, D. L. Brooks, L. P. Schwab, D. N. Parke, D. Oluwalana, D. R. Layman, M. Fan, D. L. Johnson, J. Yue, H. Smallwood, T. N. Seagroves

This study identifies CKB as a HIF-1 downstream gene promoting breast cancer metastasis and shows cyclocreatine therapy reduces invasion and enhances chemotherapy efficacy.

bioRxiv · Sep 9, 2021Cancer Biology