Structural basis of nirmatrelvir and ensitrelvir resistance profiles against SARS-CoV-2 Main Protease naturally occurring polymorphisms
G. D. Noske, E. S. Silva, M. O. Godoy…·A. S. Godoy
The paper characterizes natural polymorphisms in SARS-CoV-2 main protease and their resistance profiles against nirmatrelvir and ensitrelvir, revealing structural bases for resistance.