IL-15 re-programming compensates for NK cell mitochondrial dysfunction in HIV-1 infection
E. Moreno Cubero, S. Balint, A. Alrubayyi, A. Ogbe, R. Matthews, F. Burns, S. Rowland Jones, P. Borrow, A. Schurich, M. Dustin, D. Peppa
This study shows that IL-15 treatment improves NK cell function in HIV-1 infection by enhancing mTORC1 activity and compensating for mitochondrial dysfunction.
bioRxiv · Oct 21, 2019 · PreprintImmunology