Author

A. Sharir-Ivry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:protein sequence· 2 Approach:statistical model· 2 Approach:comparative / phylogenetic analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Y. Xia· 2 shared

Activity by Year

2019-2020 · peak 1/yr

2 papers

Recent·Most cited

Evolutionary BiologybioRxivJul 19, 2020

Quantifying Evolutionary Importance of Protein Sites: A Tale of Two Measures

Y. Xia, A. Sharir-Ivry

The paper quantifies evolutionary importance of protein sites using two measures and finds a strong linear relationship between them, with catalytic sites being an exception.

DOI 10.1371/journal.pgen.1009476

protein sequencestatistical model

𝕏 PostBluesky

Evolutionary BiologybioRxivMar 29, 2019

Non-catalytic binding sites induce weaker long-range evolutionary rate gradients than catalytic sites in enzymes

A. Sharir-Ivry, Y. Xia

The paper shows that catalytic sites in enzymes induce stronger evolutionary rate gradients than non-catalytic binding sites, suggesting catalytic optimization drives these gradients.

DOI 10.1016/j.jmb.2019.07.019

protein sequencestatistical model

𝕏 PostBluesky