Author

A. Steen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 3 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:yeast· 5 Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:imaging· 2 Approach:biophysical modeling· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

L. M. Veenhoff· 4 shared I. L. Rempel· 2 shared J. C. Wolters· 2 shared M. Kaeberlein· 2 shared M. M. Crane· 2 shared P. Gallardo· 2 shared P. R. Onck· 2 shared S. N. Mouton· 2 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersCell Biology

L. M. Veenhoff

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Imaging-Based Quantitative Assessment of Biomolecular Condensates in vitro and in Cells

T. Bergsma, A. Steen, J. Kamenz, P. Gallardo, L. M. Veenhoff

The paper introduces PhaseMetrics, an image analysis pipeline for quantifying biomolecular condensates in vitro and in cells, showing its accuracy across different experimental systems.

bioRxiv · May 22, 2024 · PreprintBiochemistry

Nucleoporin Nsp1 surveils the phase state of FG-Nups

T. A. Otto, T. Bergsma, M. Dekker, S. Mouton, P. Gallardo, J. C. Wolters, A. Steen, P. R. Onck, L. L. Veenhoff

The paper shows that Nsp1 modulates FG-Nup phase separation and its loss mimics aging phenotypes in yeast.

bioRxiv · Mar 31, 2023Cell Biology

Nuclear transport under stress phenocopies transport defects in models of C9Orf72 ALS

M. F. Semmelink, H. Jafarinia, J. C. Wolters, T. Gheorghe, S. N. Mouton, A. Steen, P. R. Onck, L. M. Veenhoff

This study shows polyPR directly affects nuclear transport via NTRs, while polyGA impacts cellular energy state, leading to similar transport defects as stress conditions.

bioRxiv · Apr 13, 2022 · PreprintCell Biology

A physicochemical roadmap of yeast replicative aging

S. N. Mouton, D. Thaller, M. M. Crane, I. L. Rempel, A. Steen, M. Kaeberlein, C. P. Lusk, A. Boersma, L. M. Veenhoff

This study measures physicochemical changes in yeast cells during replicative aging, finding acidification and organellar crowding contribute to homeostatic decline.

bioRxiv · Nov 29, 2019Biophysics

Age-dependent deterioration of nuclear pore assembly in mitotic cells decreases transport dynamics

I. L. Rempel, M. M. Crane, A. Mishra, D. P. Jansen, G. Janssens, P. Popken, M. Kaeberlein, E. van der Giessen, P. Onck, A. Steen, L. M. Veenhoff

This study shows that ageing mitotic cells experience reduced NPC component abundance and misassembled NPCs, leading to decreased nuclear transport and increased compartmentalization.

bioRxiv · Nov 24, 2018Cell Biology