A. Mishra

Investigating Quinclorac Binding to Human Serum Albumin using Spectroscopy and Molecular Docking

This study investigates quinclorac binding to human serum albumin using spectroscopy and molecular docking, revealing high-affinity binding and identifying Sudlow site I as the primary binding site.

HOXA10 is a Temporal Switch in Controlling Decidual Inflammation and Its Dysregulation is Associated with Early Pregnancy Loss

This study identifies HOXA10 as a temporal switch regulating decidual inflammation, showing its dysregulation contributes to early pregnancy loss in mice and humans.

Nanofluid-Enhanced Laser Lithotripsy Using Conducting Polymer Nanoparticles

This paper enhances laser lithotripsy efficiency using a PEDOT:PSS nanofluid, achieving significant improvements in stone ablation without increased thermal injury.

An early, novel arginine methylation of KCa3.1 attenuates subsequent T cell exhaustion.

The paper shows that early arginine methylation of KCa3.1 limits Ca2+-mediated NFAT1 activation, preventing T cell exhaustion during activation.

A novel micronemal protein, Scot1, is essential for apicoplast biogenesis and liver stage development in Plasmodium berghei

This paper identifies Scot1, a micronemal protein essential for late liver-stage development and apicoplast biogenesis in Plasmodium berghei, showing its potential as a target for malaria vaccines.

Valproic Acid Treatment Enhances Chromosome Flexibility and Electron Transport in MCF7 Breast Cancer Cells

This study examines how Valproic Acid affects chromosome flexibility and electron transport in MCF7 breast cancer cells using atomic force microscopy and electron transport analysis.

Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis product

This study uses high-throughput microfluidic technology to enrich CTCs from large blood volumes, enabling detailed molecular and morphological analysis of tumor cells in metastatic cancer patients.

SbPIP2 Mediated Improvements in Plant Resilience: Physiological and Molecular Insights into Abiotic Stress Response

This study shows that overexpressing SbPIP2 improves plant resilience to abiotic stress by reducing ROS, enhancing growth, and modulating ABA signaling pathways.

Innate floral object identification in the generalist solitary hoverfly pollinator Eristalinus aeneus

This study shows how the hoverfly Eristalinus aeneus uses innate integration of olfactory and visual cues to identify multiple floral species without prior experience.

Candida albicans' inorganic phosphate transport and evolutionary adaptation to phosphate scarcity

This study identifies phosphate transporters in Candida albicans and shows how mutations in these genes affect growth and stress resistance under phosphate scarcity.

Local adaptation to mercury contamination by nitrogen-fixing rhizobia is driven by horizontal gene transfer, copy number, and enhanced gene expression

This study identifies that horizontal gene transfer, copy number, and enhanced expression of the Mer operon confer mercury tolerance in rhizobia, with implications for plant-metal interactions.

Arrested Agonist Paradigm For Selective Radiosensitization of Prostate Cancer

This paper identifies hydroxyflutamide as an AR arrested agonist that induces DNA damage in prostate cancer cells, enabling selective radiosensitization without promoting growth.

Autophagy protein Atg7 is essential and druggable for maintaining malaria parasite cellular homeostasis and organelle biogenesis

This study shows that Atg7 is essential for malaria parasite development and identifies compounds that inhibit its function, suggesting it as a potential drug target.

SwrA extends DegU over an UP element to activate flagellar gene expression in Bacillus subtilis

The paper shows SwrA extends DegU binding over a UP element to activate flagellar gene expression in Bacillus subtilis, enabling motility and swarming.

A Microfluidic Transistor for Liquid Signal Processing

This paper introduces a microfluidic transistor that mimics electronic transistor behavior, enabling fluidic circuit design for liquid signal processing and single-particle manipulation.

A Gallium-68-Labeled Peptide Radiotracer For CD38-Targeted Imaging In Multiple Myeloma With PET

This paper develops a gallium-68-labeled peptide radiotracer, [68Ga]Ga-AJ206, for non-invasive CD38 imaging in multiple myeloma using PET, showing high specificity and utility in monitoring therapy response.

Multiplexed fluorescence and scatter detection with single cell resolution using on-chip fiber optics for droplet microfluidic applications

The paper introduces OptiDrop, a platform that enables multi-parametric optical sensing of microfluidic droplets with single-cell resolution using on-chip fiber optics.

Evolution of mate harm resistance in females from Drosophila melanogaster populations selected for faster development and early reproduction

This study shows that female mate harm resistance decreases in Drosophila melanogaster populations selected for faster development and early reproduction, likely due to changes in breeding ecology and male trait evolution.

Functional mRNA delivery to hematopoietic stem and progenitor cells in vivo.

This study demonstrates in vivo delivery of functional mRNA to hematopoietic stem cells (HSC) using lipid nanoparticles, achieving transfection in ~25% of mouse HSC with potential for therapeutic applications.

Glucuronoxylomannan intranasal challenge prior to Cryptococcus neoformans pulmonary infection enhances cerebral cryptococcosis in rodents

This study shows that intranasal GXM administration before C. neoformans infection increases fungal burden in lungs and enhances brain invasion by disrupting the blood-brain barrier.

Experimental and In Silico interaction studies of Alpha Amylase-Silver nanoparticle: a nano-bio-conjugate

The paper investigates the biosynthesis of silver nanoparticles using alpha amylase and studies their interaction with the enzyme through experimental and computational methods.

Loss of HOXA10 causes endometrial hyperplasia progressing to endometrial cancer

This study shows that reduced HOXA10 expression in mice leads to endometrial hyperplasia and cancer progression with age.

Effect of ambient fluid rheology on oscillatory instabilities in filament-motor systems

This study investigates how fluid rheology affects oscillatory instabilities in filament-motor systems using stability analysis and numerical simulations.

Description of Pectobacterium pacificum sp. nov. isolated from Colocasia esculenta

The paper describes a novel bacterial species, Pectobacterium pacificum, isolated from taro fields in Hawaii, using a polyphasic taxonomic approach.

Evaluation of Correlation between CD44, Radiotherapy Response and Survival Rate in Patients with Advanced Stage of Head and Neck Squamous Cell Carcinoma (HNSCC)

Natural infection of SARS-CoV-2 delta variant in Asiatic lions (Panthera leo persica) in India

The paper reports the detection of SARS-CoV-2 delta variant in Asiatic lions in India and its genetic similarity to local human isolates.

Selective nuclear export of mRNAs is promoted by DRBD18 in Trypanosoma brucei

This study identifies DRBD18 as a regulator of selective mRNA nuclear export in Trypanosoma brucei by promoting mRNP mobilization through the nuclear pore complex.

Ubiquitination is essential for recovery of cellular activities followingheat shock

The paper shows that stress-induced ubiquitination is essential for recovery of cellular activities following heat stress.

Baseline cell proliferation rates and response to UV differ in Lymphoblastoid Cell Lines derived from healthy individuals of extreme constitution types

The paper compares baseline cell proliferation rates and UV response in Lymphoblastoid Cell Lines from healthy individuals with different constitution types, finding significant differences in proliferation and recovery.

Desiccation stress acts as cause as well as cost of dispersal in Drosophila melanogaster

This study investigates how desiccation stress influences dispersal in Drosophila melanogaster, finding it acts as both a cause and cost, with sex-specific effects.