Author

A. T. Ayoub

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Savarino· 1 shared B. Lucic· 1 shared C. J. Neufeldt· 1 shared D. Havelka· 1 shared F. Apollonio· 1 shared I. L. Shytaj· 1 shared J. A. Tuszynski· 1 shared J. Prusa· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Savarino

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

MicrobiologybioRxivMar 9, 2021

The FDA-approved drug cobicistat synergizes with remdesivir to inhibit SARS-CoV-2 replication

I. L. Shytaj, M. Fares, B. Lucic…·M. Lusic

This study shows that cobicistat synergizes with remdesivir to inhibit SARS-CoV-2 replication in cell lines and organoids, reducing viral replication to levels comparable to uninfected cells.

DOI 10.1128/mbio.03705-21

humanexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintJan 29, 2019

Tubulin as a sensitive target of nanosecond-scale intense electric field: quantitative insights from molecular dynamics simulations

P. Marracino, D. Havelka, J. Prusa…·M. Cifra

This study uses molecular dynamics simulations to show that intense nanosecond electric fields can alter β-tubulin conformations and drug binding sites, suggesting potential for modulating microtubule dynamics.

DOI 10.1101/533984

protein structuremechanistic / dynamical model

𝕏 PostBluesky