Author

M. Fares

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Benchoua· 1 shared A. Savarino· 1 shared A. T. Ayoub· 1 shared B. Lucic· 1 shared C. Boissart· 1 shared C. J. Neufeldt· 1 shared C. Montero-Menei· 1 shared G. Gonzalez· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Benchoua

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The FDA-approved drug cobicistat synergizes with remdesivir to inhibit SARS-CoV-2 replication

I. L. Shytaj, M. Fares, B. Lucic, L. Gallucci, M. M. Tolba, L. Zimmermann, A. T. Ayoub, M. Cortese, C. J. Neufeldt, V. Laketa, P. Chlanda, O. T. Fackler, S. Boulant, R. Bartenschlager, M. Stanifer, , M. Lusic

This study shows that cobicistat synergizes with remdesivir to inhibit SARS-CoV-2 replication in cell lines and organoids, reducing viral replication to levels comparable to uninfected cells.

bioRxiv · Mar 9, 2021Microbiology

Pathological modeling of TBEV infection reveals differential innate immune responses in human neurons and astrocytes that correlate with their susceptibility to infection.

M. Fares, M. Cochet-Bernoin, G. Gonzalez, C. Montero-Menei, O. Blanchet, A. Benchoua, C. Boissart, S. Lecollinet, J. Richardson, N. Haddad, M. Coulpier

This study establishes an in vitro model of TBEV infection in human brain cells, revealing differential innate immune responses in neurons and astrocytes that correlate with their susceptibility to the virus.

bioRxiv · Oct 25, 2019Microbiology

Intrinsic adaptive value and early fate of gene duplication revealed by a bottom-up approach

G. Rodrigo, M. Fares

This paper shows gene duplication provides a small selective advantage by improving phenotypic accuracy through reduced molecular noise and suboptimal regulation, influencing its early fate in populations.

bioRxiv · Jun 19, 2017Evolutionary Biology