MicrobiologybioRxiv
Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge
M. W. Grunst, H. M. Gil, A. G. Grandea…·D. T. Evans
This study shows that potent antibody-dependent cellular cytotoxicity (ADCC) by a V2-specific antibody is insufficient to protect macaques against SIV challenge, but reduced viral loads were observed with a neutralization-sensitive SIV variant.
DOI 10.1371/journal.ppat.1011819