Author

A. Thalakola

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Biology Disciplines

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

C. Jiang· 1 shared G. M. DeNicola· 1 shared M. Teng· 1 shared N. P. Ward· 1 shared N. Prieto-Farigua· 1 shared Y. P. Kang· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

C. Jiang

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1 paper

Recent·Most cited

Cancer BiologybioRxivMar 8, 2022

A CRISPR screen identifies redox vulnerabilities for KEAP1/NRF2 mutant non-small cell lung cancer

C. Jiang, N. P. Ward, N. Prieto-Farigua…·G. M. DeNicola

This study uses a CRISPR screen to identify redox vulnerabilities in KEAP1/NRF2 mutant NSCLC, finding that SOD2 loss enhances the efficacy of β-Lapachone by disrupting mitochondrial function.

DOI 10.1016/j.redox.2022.102358

humangenetic perturbation / CRISPR

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