Author

A. Thole

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Godfrey· 1 shared B. O'Keefe· 1 shared B. Thibault· 1 shared C. A. LeClair· 1 shared C. Basset· 1 shared C. Hendrich· 1 shared D. Frey· 1 shared D. Lo· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioengineering

A. Godfrey

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics

S. G. Borhani, M. Z. Levine, L. H. Krumpe, J. Wilson, C. Hendrich, B. O'Keefe, D. Lo, G. Sittampalam, A. Godfrey, R. D. Lunsford, V. Mangalampalli, D. Tao, C. A. LeClair, A. Thole, D. Frey, , G. Rao

This paper describes a cell-free biomanufacturing approach for rapid production of griffithsin, a broad-spectrum antiviral protein, demonstrating its efficacy against SARS-CoV-2 and HIV-1.

bioRxiv · Dec 19, 2022Bioengineering

The lipid kinase PI3Kα is required for the cohesion and survival of cancer cells disseminated in serous cavities.

B. Thibault, A. Thole, C. Basset, J. Guillermet-Guibert

This study shows that PI3Kα is essential for the cohesion and survival of cancer cells in serous cavities, suggesting it as a therapeutic target.

bioRxiv · Oct 1, 2021 · PreprintCancer Biology