Author

A. Trapp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

V. N. Gladyshev· 4 shared A. Seluanov· 3 shared S. Emmrich· 3 shared V. Gorbunova· 3 shared F. Tolibzoda Zakusilo· 2 shared M. E. Straight· 2 shared M. G. Drage· 2 shared M. Mariotti· 2 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCell Biology

V. N. Gladyshev

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Multi-omic rejuvenation and lifespan extension upon exposure to youthful circulation

B. Zhang, D. E. Lee, A. Trapp, A. Tyshkovskiy, A. T. Lu, A. Bareja, C. Kerepesi, L. H. McKay, A. V. Shindyapina, S. E. Dmitriev, G. S. Baht, S. Horvath, V. N. Gladyshev, J. P. White

This study shows that prolonged heterochronic parabiosis reduces biological age and extends lifespan in mice through long-term epigenetic and transcriptomic changes.

bioRxiv · Nov 11, 2021Cell Biology

Naked mole-rat hematopoietic stem and progenitors are highly quiescent with an inherent myeloid bias

S. Emmrich, A. Trapp, F. Tolibzoda Zakusilo, M. Mariotti, M. E. Straight, Z. Zhang, S. Gray, M. G. Drage, Z. Ke, M. Takasugi, J.-H. Klusmann, V. N. Gladyshev, A. Seluanov, V. Gorbunova

This study identifies unique hematopoietic features in naked mole-rats, including myeloid bias and quiescent stem cells, linked to their exceptional longevity.

bioRxiv · Aug 1, 2021Cell Biology

Ectopic cervical thymi and no thymic involution until midlife in naked mole-rats

S. Emmrich, F. Tolibzoda Zakusilo, A. Trapp, X. Zhou, Q. Zhang, E. M. Irving, M. G. Drage, Z. Zhang, V. N. Gladyshev, A. Seluanov, V. Gorbunova

This study shows that naked mole-rats lack thymic involution until midlife and have ectopic cervical thymi with distinct T cell composition compared to mice.

bioRxiv · Aug 1, 2021Immunology

The hematopoietic landscape at single-cell resolution reveals unexpected stem cell features in naked mole-rats

S. Emmrich, M. Mariotti, M. Takasugi, M. E. Straight, A. Trapp, V. N. Gladyshev, A. Seluanov, V. Gorbunova

This study profiles the hematopoietic system of naked mole-rats at single-cell resolution, revealing unique stem cell features associated with longevity and cancer resistance.

bioRxiv · Nov 29, 2019 · PreprintImmunology