Cancer BiologybioRxiv
Transcriptional overlap links DNA hypomethylation with DNA hypermethylation at adjacent promoters in cancer
J. S. Fain, A. Loriot, A. Diacofotaki…·C. De Smet
The paper shows that DNA hypomethylation in tumors can lead to hypermethylation of adjacent promoters through overlapping transcription, linking two opposite epigenetic changes in cancer.
DOI 10.1038/s41598-021-96844-0