Author

A. Vuorinen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. O'Mahony· 1 shared A. P. Snijders· 1 shared A. Powell· 1 shared A. Russell· 1 shared C. R. Kennedy· 1 shared D. Conole· 1 shared D. Gracias· 1 shared D. House· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. O'Mahony

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A chemoproteomic platform for reactive fragment profiling against the deubiquitinases

R. Cookson, A. Vuorinen, J. Pettinger, C. R. Kennedy, J. M. Kirkpatrick, R. E. Peltier-Heap, A. Powell, A. P. Snijders, M. Skehel, D. House, K. Rittinger, J. T. Bush

The paper develops a chemoproteomics workflow to screen covalent fragments against DUB enzymes, validating four hits using biochemical assays.

bioRxiv · Feb 1, 2023 · PreprintBiochemistry

A novel tubulin binding molecule drives differentiation of acute myeloid leukaemia cells

T. R. Jackson, A. Vuorinen, L. Josa-Cullere, K. S. Madden, D. Conole, T. J. Cogswell, I. V. L. Wilkinson, L. M. Kettyle, D. Zhang, A. O'Mahony, D. Gracias, L. McCall, R. Westwood, G. C. Terstappen, S. G. Davies, , T. Milne

The paper identifies a novel tubulin-binding molecule that induces differentiation in AML cells, reducing tumour burden and improving survival in vivo.

bioRxiv · Jun 3, 2021 · PreprintCancer Biology