Frequent transitions in self-assembly across the evolution of a central metabolic enzyme
F. L. Sendker, T. Schlotthauer, C.-N. Mais, Y. K. Lo, M. Girbig, S. Bohn, T. Heimerl, D. Schindler, A. Weinstein, B. P. Metzger, J. W. Thornton, A. Pillai, G. Bange, J. Schuller, G. Hochberg
The paper investigates the evolutionary dynamics of self-assembly in prokaryotic citrate synthases, finding frequent transitions between different assembly types without strong functional consequences.
bioRxiv · Jul 5, 2024Evolutionary Biology