Author

M. Girbig

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Research Focus:protein structure prediction· 1 Organism:yeast· 1

Frequent Co-Authors

A. Brockmeyer· 1 shared A. Musacchio· 1 shared A. P. Carter· 1 shared A. Perrakis· 1 shared C. W. Mueller· 1 shared D. Libri· 1 shared E. d'Amico· 1 shared F. Mueller· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. Brockmeyer

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2 papers

Recent·Most cited

Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly-dT termination signals

M. Girbig, J. Xie, H. Groetsch, D. Libri, O. Porrua, C. W. Mueller

The paper reports cryo-EM structures of the yeast Pol III pre-termination complex and identifies key residues involved in poly-dT termination signal recognition and pausing.

bioRxiv · Feb 28, 2022Biochemistry

Conformational transitions of the mitotic adaptor Spindly underlie its interaction with Dynein and Dynactin

E. d'Amico, M. Ud Din Ahmad, V. Cmentowski, M. Girbig, F. Mueller, S. Wohlgemuth, A. Brockmeyer, S. Maffini, P. Janning, I. R. Vetter, A. P. Carter, A. Perrakis, A. Musacchio

The paper shows Spindly adopts a closed conformation that blocks Dynein-Dynactin binding, and mutations induce an open state that enables interaction, with kinetochores promoting Spindly activation.

bioRxiv · Feb 2, 2022Biochemistry