Single-Cell Transcriptomic Analysis of Livers During NLRP3 Inflammasome Activation Reveals a Novel Immune Niche
D. M. Calcagno, A. Chu, S. Gaul, N. Taghdiri, A. Toomu, A. Leszczynska, B. Kaufmann, A. Wree, L. Geisler, H. M. Hoffman, A. E. Feldstein, K. R. King
This study uses single-cell transcriptomics to show NLRP3 activation in mice causes chronic extramedullary myelopoiesis and fibrosis in the liver.
bioRxiv · Mar 31, 2021 · PreprintImmunology