Author

S. Gaul

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Wirth· 2 shared B. Isermann· 2 shared J.-N. Boeckel· 2 shared K. Shahzad· 2 shared M. Freichel· 2 shared S. Fatima· 2 shared U. Laufs· 2 shared A. Chu· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

A. Wirth

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Membrane-bound Interleukin-1α mediates leukocyte adhesion during atherogenesis

C. Maeder, T. Speer, M. Freichel, A. Wirth, J.-N. Boeckel, K. Shahzad, S. Fatima, B. Isermann, U. Laufs, S. Gaul

This study shows that membrane-bound IL-1α promotes leukocyte adhesion in atherosclerosis, while IL-1β and NLRP3 do not show similar protection.

bioRxiv · May 31, 2023Immunology

A novel nongenetic murine model of hyperglycemia and hyperlipidemia-associated aggravated atherosclerosis

S. Gaul, K. Shahzad, R. Medert, I. Gadi, C. Meader, D. Schumacher, A. Wirth, S. Ambreen, S. Fatima, J.-N. Boeckel, H. Khawaja, J. Haas, M. Brune, P. P. Nawroth, B. Isermann, , M. Freichel

This paper establishes a nongenetic mouse model to study atherosclerosis under hyperlipidemia and hyperglycemia conditions and evaluates diet effects on plaque severity.

bioRxiv · Nov 11, 2021 · PreprintPharmacology & Toxicology

Single-Cell Transcriptomic Analysis of Livers During NLRP3 Inflammasome Activation Reveals a Novel Immune Niche

D. M. Calcagno, A. Chu, S. Gaul, N. Taghdiri, A. Toomu, A. Leszczynska, B. Kaufmann, A. Wree, L. Geisler, H. M. Hoffman, A. E. Feldstein, K. R. King

This study uses single-cell transcriptomics to show NLRP3 activation in mice causes chronic extramedullary myelopoiesis and fibrosis in the liver.

bioRxiv · Mar 31, 2021 · PreprintImmunology