Dihydroceramide desaturase promotes the formation of intraluminal vesicles and inhibits autophagy to increase exosome production
C.-Y. Wu, J.-G. Jhang, W.-S. Lin, C.-W. Lin, L.-A. Chu, A.-S. Chiang, H.-C. Ho, C.-C. Chan, S.-Y. Huang
This study shows that DEGS1/Ifc promotes exosome production by enhancing intraluminal vesicle formation and inhibiting autophagic degradation of multivesicular endosomes in Drosophila.
bioRxiv · Nov 10, 2020Cell Biology