Pharmacology & ToxicologybioRxivPreprint
2-bromo-2',5'-dihydroxychalcone analogue Inhibits Endothelial Migration by Targeting VEGF-induced ERK 1/2 Phosphorylation
Aamir Hussain, Joseph Festa, Harprit Singh
This paper evaluates a 2-bromo-2',5'-dihydroxychalcone analogue (AH9) for its ability to inhibit endothelial cell migration by blocking VEGF-induced ERK1/2 phosphorylation, showing comparable efficacy to Sorafenib.
DOI 10.1101/2023.09.11.557154