Evolutionary BiologybioRxiv
Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humans.
Aaron J Sams, Anne Dumaine, Johann Nédélec…·Luis B Barreiro
The paper identifies a Neandertal haplotype at the OAS locus that affects innate immune responses by altering OAS gene expression and splice variants in humans.
DOI 10.1186/s13059-016-1098-6