BioinformaticsPLoS Computational BiologyPeer-reviewed
A dose-response model for statistical analysis of chemical genetic interactions in CRISPRi screens
Sanjeevani Choudhery, Michael A. DeJesus, Aarthi Srinivasan…·Thomas R. Ioerger
This paper introduces CRISPRi-DR, a dose-response model to analyze chemical-genetic interactions in CRISPRi screens, showing improved precision over existing methods.