ImmunologyFrontiers in ImmunologyPeer-reviewed
Exploitation of CD3ζ to enhance TCR expression levels and antigen-specific T cell function
Abdullah Degirmencay, Sharyn Thomas, Angelika Holler…·Hans J. Stauss
This study shows that CD3ζ enhances TCR surface expression and function in human T cells by increasing endogenous TCRβ expression and reducing mispairing with endogenous chains.
10 citations