Molecular BiologyJournal of Biological ChemistryPeer-reviewed
Age-dependent topoisomerase I depletion alters recruitment of rDNA silencing complexes
Lindsey N. Power, Natalia Zawrotna, Manikarna Dinda…·Jeffrey S. Smith
The paper identifies topoisomerase I (Top1) depletion in aging yeast cells and shows its impact on rDNA silencing and replicative lifespan.
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