Comprehensive healthspan assessments and influence of sex as a biological variable in aging rats
Abhishek Chandra, Zaira Aversa, Xu Zhang, Joshua N. Farr, Achudhan David, Ritika Sharma, Tamar Tchkonia, James L. Kirkland, Paul D. Robbins, Laura J. Niedernhofer, Diana Jurk, João F. Passos, David G. Monroe, Jordan D. Miller, Nathan K. LeBrasseur, , Robert J. Pignolo
This study presents a longitudinal assessment of age-related changes in Brown-Norway rat physiology and histopathology at 6, 17, and 27 months of age to provide healthspan parameters for aging research.
bioRxiv · Sep 22, 2025 · PreprintAnimal Behavior & Cognition