Author

Adele Harman

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Aiko Iwata‐OtsuboiD· 1 shared Alyssa L. RippertiD· 1 shared Beth A. Keena· 1 shared Betsy SchmalziD· 1 shared Brian F. CorbettiD· 1 shared Brittany Osborne· 1 shared Carey‐Anne EvansiD· 1 shared Chikashi Obuse· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperGenetics

Aiko Iwata‐OtsuboORCID

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3 papers

Recent·Most cited

Physiologic variation in sperm miRNAs tune embryonic gene regulatory programs and developmental outcomes

Grace S. Lee, James P. Garifallou, Samantha L. Higgins, Katherine Z. Scaturro, Adele Harman, Taylor Miller-Ensminger, Madeline N Lamonica, Liana Savarirayan, Michael C. Golding, Colin C. Conine

The paper shows that small variations in sperm miRNAs can influence embryonic gene expression and developmental outcomes through direct and secondary mechanisms.

bioRxiv · Mar 18, 2026 · PreprintDevelopmental Biology

The glucocorticoid response element near the sphingosine-1-phopshate receptor 3 gene mitigates inflammatory processes and maladaptive behavior in females and stressed males

Brian F. Corbett, Jay Arner, Sandra Luz, Valerie Estela-Pro, Jason H. Yan, Brittany Osborne, Leonel Joannas, Jorge Henao-Mejia, Jose Castro-Vildosola, Tamara Hala, Craig H. Bassing, Adele Harman, Deanne Taylor, Seema Bhatnagar

This study shows that GR-induced S1PR3 expression reduces social anxiety and stress-induced inflammation by affecting neural coherence in rats.

bioRxiv · Jan 9, 2024 · PreprintNeuroscience

Dominant-negative mutations in CBX1 cause a neurodevelopmental disorder

Yukiko Kuroda, Aiko Iwata‐Otsubo, Kerith‐Rae Dias, Suzanna E.L. Temple, Koji Nagao, Lachlan De Hayr, Ying Zhu, Shin-Ya Isobe, Gohei Nishibuchi, Sarah K. Fiordaliso, Yuki Fujita, Alyssa L. Rippert, Samuel W Baker, Marco L. Leung, Daniel C. Koboldt, , Kosuke Izumi

This study identifies de novo CBX1 variants in three individuals with neurodevelopmental features and shows they cause dominant-negative effects by disrupting HP1β chromatin binding.

bioRxiv · Sep 29, 2020 · PreprintGenetics