Author

Agostina P. Bertolin

The Francis Crick Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Organism:human· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Berta CanaliD· 2 shared John F.X. DiffleyiD· 2 shared Anne E. EarlyiD· 1 shared Guan Hwee Bernard LeeiD· 1 shared Jingkun ZengiD· 1 shared Lucy S. DruryiD· 1 shared Masashi MinaminoiD· 1 shared Michael HowelliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Berta CanalORCID

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2 papers

Recent·Most cited

BiochemistryMolecular CellPeer-reviewedJun 26, 2025

DNA replication fork stabilization and restart mechanisms revealed by biochemical reconstitution

Berta Canal, Agostina P. Bertolin, Guan Hwee Bernard Lee…·John F.X. Diffley

This study reveals DNA replication fork stabilization and restart mechanisms using biochemical reconstitution in budding yeast.

21 citationstop 2%

yeastexperimental assay

𝕏 PostBluesky

Cell BiologyMolecular CellPeer-reviewedJun 26, 2025

The mechanism of checkpoint-dependent DNA replication fork stabilization in human cells

Agostina P. Bertolin, Berta Canal, Mona Yekezare…·John F.X. Diffley

This study identifies how the DNA damage checkpoint stabilizes replication forks by preventing excess origin firing and fork collapse through the regulation of PCNA and HLTF.

27 citationstop 2%

humanDNA methylation

𝕏 PostBluesky