Author

Ai Nguyen

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Organism:virus· 2 Approach:biophysical modeling· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Camden Trent· 2 shared Di Wu· 2 shared Grzegorz PiszczekiD· 2 shared Huaying ZhaoiD· 2 shared Peter SchuckiD· 2 shared Siddhartha AK Datta· 2 shared Agata M Czaja· 1 shared Armin N. AdlyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersBiophysics

Camden Trent

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintMay 14, 2026

Intramolecular loops control SARS-CoV-2 nucleocapsid protein self-association and nucleic acid binding dependent on phosphorylation

Ai Nguyen, Siddhartha AK Datta, Camden Trent…·Huaying Zhao

This study identifies intramolecular loops that regulate SARS-CoV-2 N-protein self-association and nucleic acid binding through phosphorylation-dependent conformational changes.

DOI 10.64898/2026.01.10.698783

virusproteomics

𝕏 PostBluesky

BiophysicseLifePeer-reviewedDec 11, 2025

Evolution of a fuzzy ribonucleoprotein complex in viral assembly

Huaying Zhao, Tiansheng Li, Sergio A. Hassan…·Peter Schuck

The paper investigates how mutations in SARS-CoV-2 N protein affect RNP formation and stability, finding convergent evolution and enhanced RNP assembly in Omicron variants.

1 citation

virusproteomics

𝕏 PostBluesky