BiophysicseLifePeer-reviewed
Mapping the Conformational Landscape of a Dynamic Enzyme by XFEL and Multitemperature Crystallography
Daniel A Keedy, Lillian R Kenner, Matthew Warkentin…·James Fraser
This study uses XFEL and multitemperature crystallography to analyze the conformational changes in cyclophilin A, revealing temperature-dependent conformational heterogeneity and a conformation shuffling model.
DOI 10.7554/elife.07574