Molecular BiologyThe EMBO JournalPeer-reviewed
Nuclear RNA export factor variant initiates piRNA-guided co-transcriptional silencing
Kensaku Murano, Yuka W. Iwasaki, Hirotsugu Ishizu…·Haruhiko Siomi
The paper identifies Nxf2 as a key component in the Piwi-piRNA pathway, showing it forms complexes that stabilize Piwi and Panx and initiate co-transcriptional silencing of target transcripts.
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