Author

Akane Osa

Innovative Genomics Institute

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Biochemistry· 1

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Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

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Anand DivakaraniD· 1 shared Daniel K. NomuraiD· 1 shared Ingrid E. WertziD· 1 shared Oscar W. Huang· 1 shared Seong Ho HongiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBiochemistry

Anand DivakaranORCID

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1 paper

Recent·Most cited

BiochemistryACS Chemical BiologyPeer-reviewedFeb 2, 2024

Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation

Seong Ho Hong, Anand Divakaran, Akane Osa…·Daniel K. Nomura

This study identifies a covalent recruiter against SKP1 for PROTAC-based protein degradation, demonstrating its efficacy in degrading BRD4 and androgen receptor via the SCF complex.

39 citationstop 4%

proteomicsexperimental assay

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