Cell BiologybioRxivPreprint
SERCA is a host target of the SARS-CoV-2 envelope protein linking calcium homeostasis to autophagy
Blanka Berta, Sarolta Tóth, Péter Lőrincz…·Rita Padányi
This study shows the SARS-CoV-2 E protein disrupts ER calcium homeostasis via SERCA inhibition, leading to autophagy-related membrane remodeling.