Rita Padányi

The paper evaluates AlphaFold's predictions of transmembrane protein complexes, finding that while most show plausible membrane geometry, some have inconsistencies and limitations in predicting lipid interactions.

This study shows the SARS-CoV-2 E protein disrupts ER calcium homeostasis via SERCA inhibition, leading to autophagy-related membrane remodeling.

This study shows PMCA4b promotes epithelial cell polarization and lumen formation, with implications for cancer progression.

The paper evaluates AlphaMissense's performance in predicting pathogenicity of missense variants across diverse protein groups and introduces a web resource for access.