Author
University of Eastern FinlandORCID 0000-0003-4196-4204Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
6 papers
Recent·Most cited
Eleni Georgiou, Tuomo Laitinen, Antti Poso…·Christopher R. M. Asquith
This study identifies and optimizes a submicromolar PKN3 inhibitor, 6e (URS03-06), for cellular biology research.
Marwah Karim, Manjari Mishra, Chieh‐Wen Lo…·Shirit Einav
RMC-113 inhibits PIP4K2C and PIKfyve, reversing SARS-CoV-2-induced autophagic flux impairment and showing antiviral effects.
Abdelhakim Boudrioua, Joe D. Joiner, Iwan Grin…·Samuel Wagner
The paper identifies a synthetic small molecule, C26, that inhibits HilD, a key regulator of Salmonella secretion systems, thereby preventing bacterial invasion of host cells.
Christopher R. M. Asquith, Michael P. East, Tuomo Laitinen…·Gary L. Johnson
The paper identifies and optimizes narrow-spectrum TLK2 inhibitors using QSAR analysis and structural studies.
Marcel Rak, Amelie Menge, Roberta Tesch…·Stefan Knapp
This study develops selective MST3/4 kinase inhibitors and demonstrates their distinct cellular effects compared to MST1/2 inhibition.
Ashik Jawahar Deen, Simone Adinolfi, Jouni Härkönen…·Anna–Liisa Levonen
This study shows that KEAP1 mutations in lung cancer activate TRAF2-NFκB signaling, enhancing cell survival by preventing apoptosis.