GeneticsMolecular Therapy — Methods & Clinical DevelopmentPeer-reviewed
Inhibition of cathepsin B blocks amyloidogenesis in the mouse models of neurological lysosomal diseases mucopolysaccharidosis type IIIC and sialidosis
Gustavo Monteiro Viana, Xuefang Pan, Shuxian Fan…·Alexey V. Pshezhetsky
This study shows that inhibiting cathepsin B reduces amyloid deposits in mouse models of lysosomal diseases, suggesting it as a potential therapeutic target.
2 citations